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Gilles Hanton Selected Research

CI 1044

6/2008Characterisation of the vascular and inflammatory lesions induced by the PDE4 inhibitor CI-1044 in the dog.
11/2007Investigation of the molecular mechanisms preceding PDE4 inhibitor-induced vasculopathy in rats: tissue inhibitor of metalloproteinase 1, a potential predictive biomarker.
1/2007Altered gene expression in rat mesenteric tissue following in vivo exposure to a phosphodiesterase 4 inhibitor.

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Gilles Hanton Research Topics

Disease

5Necrosis
08/2008 - 02/2004
3Pulmonary Hypertension
01/2009 - 11/2006
3Hypoxia (Hypoxemia)
01/2009 - 12/2005
3Cardiotoxicity
08/2008 - 01/2004
3Vascular System Injuries
06/2008 - 01/2007
2Inflammation (Inflammations)
06/2008 - 11/2007
1Vascular Remodeling
01/2009
1Fibrosis (Cirrhosis)
08/2008
1Acute-Phase Reaction
06/2008
1Arteritis
06/2008
1Asthma (Bronchial Asthma)
11/2007
1Chronic Obstructive Pulmonary Disease (COPD)
11/2007
1Ischemia
08/2007
1Tyrosinemias (Tyrosinemia)
03/2007
1Lipidoses
10/2006
1Drug-Related Side Effects and Adverse Reactions
04/2006
1Tachycardia (Tachyarrhythmias)
02/2005
1Fatty Liver
02/2004
1Ketosis
02/2004

Drug/Important Bio-Agent (IBA)

4Pharmaceutical PreparationsIBA
01/2009 - 02/2005
3CI 1044IBA
06/2008 - 01/2007
3Phosphodiesterase 4 InhibitorsIBA
06/2008 - 01/2007
2Dexfenfluramine (Redux)IBA
01/2009 - 11/2006
2Minoxidil (Rogaine)FDA LinkGeneric
08/2008 - 01/2004
2Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
06/2008 - 01/2007
2Proteins (Proteins, Gene)FDA Link
06/2008 - 11/2007
2EthionineIBA
03/2007 - 02/2004
2Thioacetamide (Thioacetamid)IBA
03/2007 - 02/2004
2allyl formateIBA
10/2006 - 02/2004
2CreatineIBA
10/2006 - 02/2004
1MitogensIBA
01/2009
1rho-Associated KinasesIBA
01/2009
1Appetite Depressants (Anorectics)IBA
01/2009
1Serotonin (5 Hydroxytryptamine)IBA
01/2009
1Phosphodiesterase 3 InhibitorsIBA
06/2008
1C-Reactive ProteinIBA
06/2008
1Serum Amyloid A Protein (Serum Amyloid A)IBA
06/2008
1CytokinesIBA
11/2007
1EnzymesIBA
11/2007
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
11/2007
1Biomarkers (Surrogate Marker)IBA
11/2007
1Oxidants (Oxidizing Agents)IBA
11/2007
1Tissue Inhibitor of Metalloproteinase-1IBA
11/2007
1AntioxidantsIBA
11/2007
1Carbon MonoxideIBA
08/2007
1Tyrosine Transaminase (Tyrosine Aminotransferase)IBA
03/2007
1GalactosamineIBA
03/2007
1Isoniazid (Ftivazide)FDA LinkGeneric
03/2007
1Serotonin ReceptorsIBA
11/2006
1LipidsIBA
10/2006
1Tyrosine (L-Tyrosine)FDA Link
10/2006
1Glucose (Dextrose)FDA LinkGeneric
10/2006
1Liver GlycogenIBA
10/2006
1TaurineFDA Link
10/2006
1MonocrotalineIBA
12/2005
1Milrinone (Primacor)FDA LinkGeneric
02/2005
1Chlorpromazine (Thorazine)FDA Link
02/2004

Therapy/Procedure

1Aftercare (After-Treatment)
06/2008
1Therapeutics
11/2007